A cell-specific exosome diagnostic platform providing a noninvasive, inexpensive, and robust diagnostic tool.
At NeuroDex, we envision a world where dementia pathology is understood and patients receive personalized treatments according to their pathology
Our proprietary neuron-derived exosome isolation technology can be applied across a number of neurological indications. With our technology, a simple blood draw could allow physicians for a brain liquid biopsy
Our lead indication is Lewy Body Dementia, a poorly understood disease comprising between 6%-20% of all dementias
Increasing signal to noise ratio by utilizing cell specific exosomes, has shown an increase of over 20 fold
Leveraging regulatory FDA framework for Lab- Developed-Tests creates a quick to-market-opportunity
Capturing neuron derived exosomes enables identification of diverse pathological aspects
Use of frozen samples enables utilization of retrospective biobanks
Our data demonstrates a robust and high precision platform
We offer an isolation platform that can be combined with different detection methodologies
We have industry and academic experience in public and private diagnostic companies
Dr. Eitan was the first to study exosome...
Oded is an experienced diagnostics execu...
Christina is a Certified Public Account...
PUBLICATIONS FROM OUR TEAM
Neuronal and Astrocytic Extracellular Vesicle Biomarkers in
Blood Reflect Brain Pathology in Mouse Models of Alzheimer’s
Association of Extracellular Vesicle Biomarkers With Alzheimer Disease in the Baltimore Longitudinal Study of Aging
Plasma Extracellular Vesicles Enriched for Neuronal Origin: A Potential Window into Brain Pathologic Processes
In a randomized trial in prostate cancer patients, dietary protein restriction modifies markers of leptin and insulin signaling in plasma extracellular vesicles
Walking speed decline in older adults is associated with elevated pro-BDNF in plasma extracellular vesicles
Extracellular Vesicle-Associated Aβ Mediates Trans-Neuronal Bioenergetic and Ca2+-Handling Deficits in Alzheimer's Disease Models